Despite the general acknowledgement by the scientific community that ‘Genetics load the gun but environment pulls the trigger’ there is persistent uncertainty as to the global burden of disease attributable to environmental factors.
Throughout our lives, we are exposed to a variety of factors, both internal and external, which are a function of our lifestyle, behavior and environment. All these exposures form a concept called “the exposome”.
The concept of exposome reflects the cumulative measure of environmental influences and associated biological responses from the perinatal period onwards. Its importance to health and disease is undeniable and the exposome of each individual could completely interact with the way chronic diseases develop and evolve.