ALSPAC

“The Avon Longitudinal Study of Parents and Children (ALSPAC) is a UK-based birth cohort initiated in 1991, comprising over 14,000 children and their families. It provides rich longitudinal data on health, genetics, and environmental exposures, including detailed air pollution metrics—making it a valuable resource for investigating respiratory health across the life course.

As part of the REMEDIA project, ALSPAC data were used to explore how environmental exposures influence lung function development in youth. The analytical approach involved:

Identifying and characterizing distinct trajectories of lung function from childhood through adolescence;

Examining how air pollution and other environmental exposures are distributed across these trajectory groups;

Applying causal inference methods to investigate potential causal links between exposures and lung function evolution.

Comprehensive analyses have been conducted, and findings will be communicated in due course as part of the project’s final dissemination activities.”

Summary data table

To come…